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Recent Projects

Gene Discovery Gene Discovery

Gene Discovery
Patient cohorts, gene linkage, and cloning data provide a basis that can be maximized by utilizing bioinformatics database and modeling information.

Cell Signaling
Cell Signaling Pathways
Structural databases hold a wealth of information that can be exploited in studying protein-protein interactions within signaling complexes.
Antibody Design
Homology modeling can help refine antibody design and other protein surface dependent analyses.
Protein Structure Determination Protein Structure Determination
Protein Structure Determination
X-ray crystallography is increasingly becoming a technique accessible to the non-specialist laboratory, especially with the help of expert consultants.
Catalytic Mechanism Protein Structure Determination Protein Structure Determination

Catalytic Mechanism
Seeing how substrates and products fit into the active site, in combination with binding data, often facilitates and clarifies the understanding of catalysis.

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